Fall 2011 Agenda

Technology and Innovation Expo

The Expo was October 28, 2011 at the Dunn-Richmond Economic Development Center in Carbondale, Illinois. It featured presentations by SIU faculty inventors of new inventions and start-up businesses resulting from SIU intellectual property. The event aims to raise awareness of the important technology advancements and related business developments, as well as available opportunities, related to SIU inventions, patents and technology licensing. TIE-F11 was part of Innovation Week at SIU Carbondale.

Friday, October 28: Technology & Innovation Expo

9:00 AM Registration and Continental Breakfast
9:30 AM Welcome and Morning Address by Chancellor Rita Hartung Cheng
10:00 AM – 12:00 PM Scientist Presentations:


10:00 AM – Dr. Kathleen Campbell (School of Medicine, Springfield): D-methionine (D-met) as a Protective Agent – D-met protects against radiation-induced oral mucositis, cisplatin-induced ototoxicity and other cisplatin side effects, aminoglycoside-induced hearing loss, and noise-induced hearing loss. We have completed successful small scale Phase II clinical trials for radiation-induced oral mucositis and cisplatin-induced hearing loss which have shown significant protection with oral D-met administration. D-met also provides partial protection from aminoglycoside-induced hearing loss with no antimicrobial interference in animal studies. D-met protects against noise-induced hearing loss if given before, during or even when first started up to 7 hours after noise-cessation. The US Department of Defense has funded our Phase 2 clinical trials to test oral D-met to prevent permanent noise-induced hearing loss in soldiers during weapons training. We are currently filing our Internal Review Board (IRB) and Food and Drug Administration (FDA) documents. Our research program is currently funded by the National Institutes of Health and the US Department of Defense.


10:20 AMDr. David Lightfoot and Dr. Khalid Meksem (College of Agricultural Sciences): Soybean Cyst Nematode (SCN) and Soybean Sudden Death Syndrome – The past year has seen several breakthroughs in genetic technologies to two major soybean diseases: Soybean Cyst Nematode (SCN) and Soybean Sudden Death Syndrome. There are 3 issued patents and 3 patents pending based on gene marked loci, cloned genes and proprietary assays for selections. Transgenes are becoming available for some of the genes that were tested. A major break-through has been showing one gene provides a large amount of resistance to SDS but only a small part of resistance to SCN. The gene works better in new locations as a transgene than it does by breeding. It can save growers over $1 billion a year in crop losses.


10:40 AMDr. Yoginder “Paul” Chugh (College of Engineering, Mining and Mineral Resources Engineering): An Innovative Spray System for Control of Dust Around a Continuous Miner – During late 2010, the authors developed an innovative water spray system for continuous miner (CM) that is scientifically founded (Patent Pending) and has shown promise to reduce respirable dust exposure of mine workers by about 30%. It includes scientifically designed sprays around the cutting drum, outer bit-ring sprays, chassis sprays and side sprays. About 10–15 feet behind these sprays are additional sprays that cover the area between the CM chassis and the mine roof and sides. Based on a successful demonstration of the spray system concepts to industry on a scaled CM model, Knight Hawk Coal, LLC decided to implement the concepts on a CM in rebuild stage in cooperation with Joy. The Office of Coal Development, through the Illinois Clean Coal Institute, provided funds to support this field demonstration. The rebuilt miner returned to a Knight Hawk Coal mine in June 2011. The project team has recently completed field evaluation of the dust control performance of the rebuilt CM using gravimetric sampling and real-time monitoring using Personal Dust Monitor (PDM). The results show that the spray system is very effective in controlling respirable dust all around the mining face area. The Coal Company has already committed to install the developed the spray system on their continuous miners.



11:10 AM – Dr. Andrei Kolmakov (College of Science, Physics): Development of Techniques for Encapsulation and Electron Microscopy/Spectroscopy of Fully Hydrated Micro-samples – Many of the samples (i. e. forensic) are wet or toxic and require their collection and preservation for extended periods for later studies. Electron microscopy and spectroscopy are the key imaging and analytical tools which, however, are capable of working with dried samples under the vacuum conditions. Based on recent progress in fabrication of new electron transparent membranes, we report on development of new techniques for encapsulation and electron microscopy/ photoelectron spectroscopy of fully hydrated microscopic samples relevant to sensing, catalysis, energy and forensic applications.

11:30 AMDr. Colleen Scott (College of Science, Chemistry and Biochemistry): Spiro-Silaanthracene (Carbondale Reds) as Red and Near Infrared Sensors and Probes – The authors have developed highly fluorescent compounds with long emission wavelength for use in molecular sensing/probing of biological systems, and as fluorescent tags. Fluorescent probes that absorb and emit red or near infrared (NIR) radiation have certain advantages over their UV or visible counterparts. Specifically, red or NIR probes have better performance in biological media because there is little excitation of biological molecules in this region. Furthermore, there is less light scattering and deeper penetration in tissue with long wavelength radiation. The invention has three main advantages over the current technology. (1), a key synthetic intermediate that allows effective synthesis of a number of different biological sensors/ probes, making the invention very versatile; (2), the presence of the silicon atom will render the compounds non-toxic, thus biologically compatible; and (3) the long emission wavelength of the compounds allow probing of cellular activities without the problems of cellular auto-fluorescence and light scattering, which usually result in low imaging resolution.

12:00 PM Lunch (catered by 17th Street Barbeque), Luncheon Keynote, Awards

Keynote: Phil Pfeffer, President and CEO of Treemont Capital Inc. (bio)

1:30 – 3:00 PM University “Spin-Out” Panel; Panel Members:

Paul Nieman (Market Launchers) , Moderator

Dr. Ken Anderson (Thermaquatica)

Dr. Hurley Myers (DXR Development Group)

Dr. Bakul Dave (Enki, Nanoaqueonics)

3:00 PM Student Poster Competition Winner Announced

Saluki Innovation Lab Tour

3:30 PM Awards: Inventor, Innovator, and Start-up of the Year
Ribbon-Cutting at Saluki Innovation Lab
4:00 PM Reception (catered by Kindling and Alto Vineyards)

Register for the event.